7-Hydroxycoumarin

Product Name: 7-Hydroxycoumarin
CAS No.: 93-35-6
Chemical Name: 7-Hydroxycoumarin
Synonyms: UMBELLIFERONE;7-Hydroxycoumarine;Z-LIGUSTILIDE;SKIMMETIN;7-Hydroxy-2H-chromen-2-one;UMBELLIFERON;Dichrin A;7 HC;HYDRANGIN;Hydramgin
CBNumber: CB1854673
Molecular Formula: C9H6O3
Formula Weight: 162.14
MOL File: 93-35-6.mol

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7-Hydroxycoumarin Property

Melting point:: 230 °C (dec.)(lit.)
Boiling point:: 248.82°C (rough estimate)
Density: 1.2599 (rough estimate)
refractive index: 1.5380 (estimate)
storage temp.: 2-8°C
solubility: dioxane: soluble
pka: 7.11(at 25℃)
form: Powder and Agglomerate
color: Off-white to beige-brownish
PH Range: Non/ uorescence (6.5) to blue / uorescence (8.0)
Odor: develops odor of coumarin on heating
Water Solubility: 1 g/100 mL (100 ºC)
λmax: 320nm
Merck: 14,9847
BRN: 127683
Major Application: Fluorescent brighteners, fungicides, cosmetics, antitrypanosomal, antileishmanial activities, antifungal, antibacterial, antiinflammatory, antiHIV, detection of microorganisms, treatment of impaired neurotransmission disorders, Alzheimer’s disease, vascular and lymphatic edema cancer, early diagnosis of stroke, dental material, drug-coated coronary stent system
InChIKey: ORHBXUUXSCNDEV-UHFFFAOYSA-N
LogP: 1.580 (est)
CAS DataBase Reference: 93-35-6(CAS DataBase Reference)
NIST Chemistry Reference: 7-Hydroxycoumarin(93-35-6)
EPA Substance Registry System: Umbelliferone (93-35-6)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
RTECS: GN6820000
HS Code: 29322980
Toxicity: LD50 intravenous in mouse: 450mg/kg

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 93979
Product name: Umbelliferone
Purity: suitable for fluorescence indicator, ≥98.0% (HPLC)
Packaging: 25g
Price: $111
Updated: 2024/03/01

Sigma-Aldrich

Product number: 54826
Product name: Umbelliferone
Purity: analytical standard
Packaging: 50mg
Price: $140
Updated: 2024/03/01

TCI Chemical

Product number: H0236
Product name: Umbelliferone
Purity: >98.0%(GC)
Packaging: 5g
Price: $31
Updated: 2024/03/01

TCI Chemical

Product number: H0236
Product name: Umbelliferone
Purity: >98.0%(GC)
Packaging: 25g
Price: $60
Updated: 2024/03/01

Alfa Aesar

Product number: L04082
Product name: 7-Hydroxycoumarin, 98%
Packaging: 25g
Price: $68.7
Updated: 2024/03/01

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7-Hydroxycoumarin Chemical Properties,Usage,Production

Chemical Properties

Light Brownish Powder

Uses

A metabolite of Coumarin. The aglucon of skimmin. Present in many plants

Uses

antifungal, phytoalexin

Uses

7-Hydroxycoumarin is used as an intracellular pH sensitive fluorescent indicator & bloodbrain barrier probe. It is used as a sunscreen agent, and an optical brightener for textiles. It has also been used as a gain medium for dye lasers.

Uses

In sunscreen lotions and creams; as intracellular and pH sensitive fluorescent indicator and blood-brain barrier probe.

Definition

ChEBI: A hydroxycoumarin that is coumarin substituted by a hydroxy group ay position 7.

General Description

Umbelliferone is a naturally occurring coumarin, present in a variety of medicinal plants from the Apiaceae (Umbelliferae) family and also in plants from other families such as mouse-ear hawkweed.

Purification Methods

It crystallises from water (m 232-232.2o) or EtOH (m 232o). It sublimes at 160o/0.001mm. Fluorescence: Em max 452nm/Exc 325nm in 50% EtOH. [Beilstein 18 H 27, 18 I 306, 18 II 16, 18 III/IV 294, 18/1 V 386.]

7-Hydroxycoumarin Preparation Products And Raw materials

Raw materials

2,4-Dihydroxyacetophenone

Preparation Products

[(2-OXO-2H-CHROMEN-7-YL)OXY]ACETIC ACID 8-ACETYL-6-HYDROXY-7-METHOXY-CHROMEN-2-ONE 7-ACETOXYCOUMARIN CHEMBRDG-BB 6088138 FRAXIDIN 7-Methoxycoumarin 7-Ethoxycoumarin 2-(2-OXO-2H-CHROMEN-7-YLOXY)-PROPIONIC ACID 8-ACETYL-7-HYDROXYCOUMARIN 8-ACETYL-7-METHOXYCOUMARIN XANTHOTOXOL 7-ALLYLOXYCOUMARIN

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7-Hydroxycoumarin Suppliers

Americas 1 Australia 1 Belgium 3 Canada 6 China 372 Czech Republic 1 Europe 3 France 2 Germany 9 India 35 Japan 5 Poland 1 Slovakia 1 Switzerland 4 Ukraine 1 United Kingdom 22 United States 77 Global 544

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10194
Advantage: 62

HBCChem, Inc.

Tel: +1-510-219-6317
Fax: +1-650-486-1361
Email: sales@hbcchem.com
Country: United States
ProdList: 10658
Advantage: 60

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8449
Advantage: 60

Target molecule Corp.

Tel: 857-239-0968
Fax: 857-239-8801
Email: service1@targetmol.com
Country: United States
ProdList: 2559
Advantage: 60

AbaChemScene

Tel: 732-484-9848
Fax: 888-484-5008
Email: sales@chemscene.com
Country: United States
ProdList: 3986
Advantage: 60

Alfa Chemistry

Tel: +1-5166625404
Fax: 1-516-927-0118
Email: Info@alfa-chemistry.com
Country: United States
ProdList: 21317
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 19892
Advantage: 58

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6393
Advantage: 58

Accela ChemBio Inc.

Tel: (+1)-858-699-3322
Fax: (+1)-858-876-1948
Email: info@accelachem.com
Country: United States
ProdList: 19965
Advantage: 58

Alchem Pharmtech,Inc.

Tel: 8485655694
Email: sales@alchempharmtech.com
Country: United States
ProdList: 63711
Advantage: 58

Aladdin Scientific

Tel: +1-833-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57511
Advantage: 58

SLN Pharmachem

Tel: --
Fax: --
Email: slnpharmachem@vsnl.net
Country: United States
ProdList: 188
Advantage: 43

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View Lastest Price from 7-Hydroxycoumarin manufacturers

hebei hongtan Biotechnology Co., Ltd

Product: 7-Hydroxycoumarin 93-35-6
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000kg
Release date: 2024-03-19

Ouhuang Engineering Materials (Hubei) Co., Ltd

Product: 7-Hydroxycoumarine 93-35-6
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99.7%
Supply Ability: 200000kg
Release date: 2024-04-23

Henan Fengda Chemical Co., Ltd

Product: 7-Hydroxycoumarin 93-35-6
Price: US $100.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-24

93-35-6, 7-HydroxycoumarinRelated Search:

Coumarin Tetrahydro-4H-pyran-4-one Methylparaben 4-Hydroxybenzoic acid 4-Hydroxybenzaldehyde 2,2',4,4'-Tetrahydroxybenzophenone 4'-Hydroxyacetophenone 3,4-Dihydroxyacetophenone 4-Methoxyphenol CHLOROPHOSPHONAZO III Dihydrocoumarin Esculetin 6-Hydroxycoumarin DICUMAROL 4-HYDROXY MEPHENYTOIN 4-Methylumbelliferone 4-HYDROXYCOUMARIN, FOR FLUORESCENCE,4-Hydroxycoumarin99%,HydroxyCoumarin,4-HYDROXYCOUMARIN (98.0%),HYDROXYCOUMARIN, 4-(RG) 3-(α-acetonyl-2-furylmethyl)-4-hydroxycoumarin

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93-35-6

93-32-6

HOC6H3CHCHCOO